Objective To construct a safe and comfortable nursing plan for patients with prone position ventilation to provide guidance for prone position nursing practice. Methods After the review of the relevant literature and the summary of the existing research evidence，a safety and comfortable nursing plan for prone ventilation patients was preliminarily established. 2 rounds of Delphi expert inquiry were adopted，and the program items were modified according to the expert opinions. Results A total of 14 articles were included in the literature review. In the first round，17 experts were consulted，and the effective recovery rate was 94.12%. In the second round，16 experts were consulted，and the effective recovery rate was 93.75%. The 2 rounds of expert authority coefficients were 0.91 and 0.92；the Kendall harmony coefficients were 0.294（P<0.001） and 0.199（P<0.001）；the coefficient of variation of each item was 0 to 0.17；the mean value of importance assignment was 4.40 to 5.00 points. Finally，a safe and comfortable nursing plan for patients with prone ventilation was formed，including 3 first-level indicators，11 second-level indicators and 40 third-level indicators. Conclusion The safe and comfortable nursing plan for patients with prone position ventilation constructed in this study is scientific，feasible and of strong clinical practical value，and can provide guidance for clinical nursing practice.

Objective To construct an early enteral nutrition tolerance monitoring system for ICU patients and to apply it into the practice. Methods The enteral nutrition tolerance score table was revised,and on this basis,the early enteral nutrition tolerance monitoring system of ICU patients was constructed to collect relevant data in real time. Using the convenient sampling method,120 patients with early enteral nutrition treated in ICU of a tertiary A hospital in Zhejiang Province from March to August 2021 were selected as the research subjects. The monitoring system was used to evaluate the tolerance to enteral nutrition of the experimental group;the revised enteral nutrition tolerance rating scale was used to evaluate the control group;the enteral nutrition scheme was dynamically adjusted according to the evaluation results. The incidence of feeding intolerance within 7 days of enteral nutrition,the target feeding rate,and the difference of albumin,serum total protein and hemoglobin concentrations between the 8th day and the 1st day of enteral nutrition were compared between the 2 groups,and the nurses’ satisfaction with the monitoring system was collected. Results The incidence of feeding intolerance in the experimental group was lower than that in the control group;the target feeding rate was higher than that in the control group;the difference of albumin,serum total protein and hemoglobin concentrations between the 8th day and the 1st day of enteral nutrition was higher than that in the control group（P<0.05）. The total average score of nurses’ satisfaction with the monitoring system was（4.51±0.31）. Conclusion The use of early enteral nutrition tolerance monitoring system for ICU patients can effectively reduce the incidence of early enteral nutrition intolerance,improve the target feeding rate and improve the nutritional status of patients. Nurses are highly satisfied with the monitoring system.